miRNA description for LET-7D
miRNA accession	LET-7D
Species	Homo sapiens
LET-7D identified in exosomes derived from the following tissue/cell type
Breast cancer cells [Exosomes]	20976003
Breast cancer cells [Extracellular vesicles]	24468161
Breast cancer cells [Extracellular vesicles]	24468161
Dendritic cells [Exosomes]	21505438
Lung cells [Microvesicles]	20079801
Serum [Exosomes]	18589210
Serum [Exosomes]	35173168
Serum [Exosomes]	35173168
Stomach cancer cells [Exosomes]	20949044
Stomach cancer cells [Exosomes]	20949044
T cells [Exosomes]	21505438
Experiment description of studies that identified LET-7D in exosomes
1 Experiment ID 333 Identified molecule miRNA Identification method Microarray PubMed ID 20976003    Organism Homo sapiens Experiment description Selective release of microRNA species from normal and malignant mammary epithelial cells Authors Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM Journal name PLoS One Publication year 2010 Sample Breast cancer cells Sample name MCF-7 Molecules identified in the study Protein miRNA Methods used in the study Slot blot RT-PCR Microarray EV-TRACK -
2 Experiment ID 1254 Identified molecule miRNA Identification method Microarray PubMed ID 24468161    Organism Homo sapiens Experiment description Molecular characterization of exosome-like vesicles from breast cancer cells. Authors Kruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R. Journal name BMC Cancer. Publication year 2014 Sample Breast cancer cells Sample name MCF7 Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Microarray RT-PCR Western blotting EV-TRACK EV140357: EV-METRIC:22%
3 Experiment ID 1255 Identified molecule miRNA Identification method Microarray PubMed ID 24468161    Organism Homo sapiens Experiment description Molecular characterization of exosome-like vesicles from breast cancer cells. Authors Kruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R. Journal name BMC Cancer. Publication year 2014 Sample Breast cancer cells Sample name MDA-MB231 Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Microarray RT-PCR Western blotting EV-TRACK EV140357: EV-METRIC:22%
4 Experiment ID 117 Identified molecule miRNA Identification method Human miRNA Microarray Kit PubMed ID 21505438    Organism Homo sapiens Experiment description Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Authors Mittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F. Journal name NATCOM Publication year 2011 Sample Dendritic cells Sample name Dendritic cells Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Microarray EV-TRACK EV110049: EV-METRIC:11%
5 Experiment ID 324 Identified molecule miRNA Identification method Microarray or RT-PCR PubMed ID 20079801    Organism Mus musculus Experiment description Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription Authors Aliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ Journal name Exp Hematol Publication year 2010 Sample Lung cells Sample name Lung cells Molecules identified in the study Protein miRNA Methods used in the study FACS RT-PCR EV-TRACK EV100071: EV-METRIC:14%
6 Experiment ID 45 Identified molecule miRNA Identification method 467microRNA Array PubMed ID 18589210    Organism Homo sapiens Experiment description MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Authors Taylor DD, Gercel-Taylor C Journal name GO Publication year 2008 Sample Serum Sample name Serum - Papillary adenocarcinoma of ovary Molecules identified in the study Protein miRNA Methods used in the study Western blotting MicroRNA array EV-TRACK -
7 Experiment ID 2749 Identified molecule miRNA Identification method qRT-PCR PubMed ID 35173168    Organism Homo sapiens Experiment description Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Authors Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L. Journal name Nat Commun Publication year 2022 Sample Serum Sample name Healthy Molecules identified in the study miRNA Methods used in the study qRT-PCR EV-TRACK -
8 Experiment ID 2750 Identified molecule miRNA Identification method qRT-PCR PubMed ID 35173168    Organism Homo sapiens Experiment description Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Authors Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L. Journal name Nat Commun Publication year 2022 Sample Serum Sample name Breast cancer patients Molecules identified in the study miRNA Methods used in the study qRT-PCR EV-TRACK -
9 Experiment ID 88 Identified molecule miRNA Identification method Human miRNA Microarray Kit RT-PCR PubMed ID 20949044    Organism Homo sapiens Experiment description Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Authors Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, Muramatsu K, Fukuda Y, Ogura S, Yamaguchi K, Mochizuki T. Journal name PLOS1 Publication year 2010 Sample Stomach cancer cells Sample name AZ-P7a Molecules identified in the study Protein miRNA Methods used in the study Immunoelectron microscopy Western blotting RT-PCR Human miRNA Microarray Kit EV-TRACK EV100005: EV-METRIC:44%
10 Experiment ID 82 Identified molecule miRNA Identification method RT-PCR PubMed ID 20949044    Organism Homo sapiens Experiment description Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Authors Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, Muramatsu K, Fukuda Y, Ogura S, Yamaguchi K, Mochizuki T. Journal name PLOS1 Publication year 2010 Sample Stomach cancer cells Sample name AZ-521 Molecules identified in the study Protein miRNA Methods used in the study Western blotting RT-PCR Human miRNA Microarray Kit EV-TRACK EV100005: EV-METRIC:44%
11 Experiment ID 115 Identified molecule miRNA Identification method Human miRNA Microarray Kit PubMed ID 21505438    Organism Homo sapiens Experiment description Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Authors Mittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F. Journal name NATCOM Publication year 2011 Sample T cells Sample name J77 Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Microarray EV-TRACK EV110049: EV-METRIC:11%